【摘要】 目的磁共振弥散张量成像(MR-DTI)是一种新的无创性成像方法,它不同于常规T2加权成像(T2WI)和弥散加权成像(DWI),它可以准确地反映水分子扩散的方向信息,并通过特殊的软件处理,能够实现白质的纤维跟踪与可视化。本文应用磁共振扩散张量成像技术显示人脑白质纤维束,探讨其与正常解剖学描述的一致及其临床应用的可行性。方法6例志愿者,男4例,女2例,年龄范围21～62岁。于GE 1.5T Sign CV/I型磁共振扫描机,相控阵列鸟笼状头部线圈,采用单次激发回波平面弥散张量成像序列扫描,GE公司Workstation中的Functool软件进行DTI数据的后处理及三维脑白质纤维束示踪。结果能较好显示的白质纤维有:连合系、钩束、上下纵束、下额枕束、内囊等。上述纤维束与已知的解剖学上的正常的同名纤维束的描述具有较好的一致性。结论通过DTI方法,我们可以获得一套较为完整的主要正常脑白质纤维束的解剖图,该方法是一种可使脑白质束快速可视化的新方法。更多还原

【Abstract】 Objective To assess the value of white matter fiber tractography based on magnetic resonance diffusion-tensor imaging(MR-DTI),a new noninvasive technique that helps estimate the structural connectivity of the brain,in understanding the anatomy of the white matter fiber tract.Methods Six consecutive volunteers received MR-DTI examination using a GE 1.5T Sign CV/I whole-body MR system and version 2.0 Functool software for image processing.The protocol included T1WI for localization and single-shot echo-planner diffusion tensor imaging of the entire brain in axial,sagittal,and /or coronal sections.Results White matter fiber tracts imaged by MR-DTI were consistent with known white matter fiber anatomy.The major fiber tracts were well observed in all the cases.The tracts visualized included the corpus callosum,anterior commissure,uncinate fasciculus superior and inferior longitudinal fascicules,inferior occipito-frontal fasciculus,internal capsule and corona radiate.Conclusion A set of detailed white matter fiber anatomy maps of the normal brain is obtained by means of single-shot echo-planner diffusion tensor imaging at high resolution.This technique allows rapid visualization of the white matter tracts in vivo,and provides a new reliable means for studying fiber connectivity in the brain.更多还原