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旱莲草对衰老小鼠组织ATP酶、细胞形态及记忆力的研究

Evaluation of Eclipta Prostrate on Activities of Tissue ATPase,Cellular Form and Memory Behavior on Aging Mice

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【作者】 郝洪阮耀

【Author】 HAO Hong RUAN Yao (Nanyang Higher Medical College,Nanyang 473000,China)

【机构】 南阳医学高等专科学校机能学实验室南阳医学高等专科学校药理学教研室 河南南阳473058河南南阳473058

【摘要】 目的:探讨旱莲草拮抗D-半乳糖致衰老小鼠的作用。方法:给小鼠腹腔注射D-半乳糖建立衰老模型,同时以旱莲草作为抗衰老实验药物灌服。观察6周以后,与对照小鼠比较,在组织ATP酶、细胞形态、记忆力的差异。结果:旱莲草可增强小鼠脑、心内Na+-K+-ATP酶、Ca2+-APT酶活性,改善细胞形态,提高小鼠的记忆学习能力。结论:旱莲草具有一定的抗衰老作用。

【Abstract】 Objective:To observe the antiaging effects of Eclipta prostrate L on aging mice induced by D-galactose.Methods: Aging models were established with D-galactose injection.At the same time, Eclipta prostrate L as antiaging drug was used to model mice.We measured and compared the activities of tissue ATPase in brains and heart、cellular form And memory behavior between the aging mice induced by D-galactose and the control. Result:Eclipta prostrate L can improve activities of tissue ATPase in mouse brains and heart 、improve cellular form and enhance the learning memory behavior.Conclusion: Eclipta prostrate L has the antiaging effects.

【基金】 河南省科技局科研项目
  • 【文献出处】 成都中医药大学学报 ,Journal of Chengdu University of Traditional Chinese Medicine , 编辑部邮箱 ,2007年01期
  • 【分类号】R285.5
  • 【被引频次】12
  • 【下载频次】215
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