【摘要】 目的:确定猫爪草有效部位对实验动物免疫功能的影响。方法:环磷酰胺造模法制作免疫抑制小鼠模型,灌胃给药,观察和比较猫爪草多糖、皂苷对其腹腔巨噬细胞吞噬功能、溶血素形成以及外周血T淋巴细胞数的影响。结果:猫爪草多糖、皂苷可使吞噬百分率、吞噬指数显著升高;猫爪草多糖、皂苷可显著促进溶血素的形成并提高外周血中T淋巴细胞数。结论:猫爪草的有效部位对免疫抑制小鼠有免疫兴奋作用。更多还原

【Abstract】 Objective: To determine the effects of active constituent of Radix Ranunculi Ternati on immune function of experimental animal.Methods: Immune suppression mouse models were made by cyclophosphamide method.After intragastric administration,the effects of polysaccharide and saponin of Radix Ranunculi Ternati on phagocytosis of peritoneal macrophage,formation of hemolysin and T-lymphocyte population of peripheral blood were observed and compared.Results: These two active constituent can highten the percent and the index of phagocytosis,enhancement the formation of the hemolysin obviously and increase the number of T-lymphocytes in peripheral blood.Conclusion: The active part of Radix Ranunculi Ternati can stimulate the immunologic function of immune suppression mouse models.更多还原