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纳络酮加丹参注射液治疗重度新生儿HIE的临床研究

A Clinical Study on Treating Hypoxic Ischemic Encephalopathy of Newborn with Naloxone Adding Radix Salviae Miltiorrhizae Injection

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【作者】 郑智育杨明廖富强黎远团潘广赉

【Author】 ZHENG Zhiyu,YANG Ming,LIAO Fuqiang,et al.Department of Paediatrics, the People’s Hospital of Fogang County, Guangdong 511600,China

【机构】 广东省佛冈县人民医院儿科广东省佛冈县人民医院儿科

【摘要】 目的观察使用纳络酮加丹参注射液治疗重度新生儿缺氧缺血性脑病(HIE)的疗效。方法35例重度HIE患儿随机分为两组,观察组20例,对照组15例。除进行相同的常规治疗外,观察组给予纳络酮静滴,连用5d,丹参注射液加10%GS静滴,疗程28d。观察患儿临床症状的变化,并随访12个月,观察神经系统后遗症的发生率。结果观察组患儿临床症状明显改善,神经系统后遗症发生率较低。结论纳络酮加丹参注射液治疗重度新生儿HIE疗效显著。

【Abstract】 Objective Observing the effect of Naloxone adding Radix salviae miltiorrhizae in treating hypoxic ischemic encephalopathy of newborn. Methods 35 cases were randomly divided into 2 groups,which include observed group (20 cases) and control group (15 cases). Both were given general treatment, and the observed group was treated with Naloxone adding Radix salviae miltiorrhizae. Attention was paid to the changes on clinical symptoms and signs of the newborn patients. Based on a 12-month follow-up visit of all patients, observation was focused on the occurrence rate of sequelae of nerve system. Results The observed group had obvious improvement in clinical symptoms and a low occurrence rate of sequelae of nerve system. The results showed significant difference from the control group. Conclusion Treating hypoxic ischemic encephalopathy of newborn with Naloxone adding Radix salviae miltiorrhizae is effective.

  • 【文献出处】 白求恩军医学院学报 ,Journal of Bethune Military Medical College , 编辑部邮箱 ,2007年01期
  • 【分类号】R722.12
  • 【被引频次】3
  • 【下载频次】30
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