【摘要】 目的了解真菌性角膜炎病原菌的种类和构成情况,获取流行病学资料,并指导临床个体化治疗。方法对2001年1月至2005年12月在我院就诊明确诊断真菌性角膜炎的病例进行回顾性分析。结果共有239例真菌性角膜炎,共培养出真菌菌株156株,其中以镰刀菌感染(77例,49.36%)和曲霉菌感染(52例,33.33%)为主,除此之外还有白色念珠菌感染(18例,11.54%),青霉菌感染(7例,4.49%),头孢霉菌感染(2例,1.28%)。结论镰刀菌仍为目前青岛地区真菌性角膜炎的主要致病菌,但其所占比例逐年下降,曲霉菌在致病菌中的比例逐年升高。更多还原

【Abstract】 Objective To study the types and constituent ratio of pathogenic fungus in fungal keratitis,obtain epidemiological data,and guide individualized treatment. Methods A retrospective study was done for patients with a definite diagnosis as having fungal keratitis at our hospital between January 2001 and December 2005. Results Fungal keratitis were found in 239 cases,156 fungal strains were cultured,of which,Fusarium accounted for 77 cases(49.36%),Eurotium 52(33.33%),Blastomyces albicans 18(11.54%),Penicillium 7(4.49%) and Cephalosporium 2(1.28%). Conclusion Fusarium is still a dominant pathogen of fungal keratitis in Qingdao area though there is a tendency of decrease in its constituent ratio.Eurotium,with its increasing constituent ratio,is becoming an important pathogen for fungal keratitis更多还原