【摘要】 目的:探讨轻度胃肠炎伴婴幼儿良性惊厥(BICE)的临床特点及预后。方法:分析2001年11月～2006年10月轻度胃肠炎伴发无热惊厥31例患儿的临床和随访资料。结果:31例均为5～25个月的婴幼儿,12～24个月22例;均发生在秋、冬季;3天内发生惊厥29例,1次病程中惊厥平均发作1.4次,表现为全身强直-阵挛发作,发作间期脑电图仅1例呈4～5Hzθ波活动,其余脑电图均正常;脑影像学、血生化及脑脊液检查正常,惊厥停止后未行抗治疗。1例复发,复发≤2次,病程少于1年。全部病例无癫和热性惊厥家族史,精神运动发育正常。结论:轻度胃肠炎可以伴有无热惊厥,均发生在婴幼儿,多数为一过性,不需特殊治疗,预后良好。更多还原

【Abstract】 Objective:To investigate the clinical features and the prognosis of benign infantile convulsions associated with mild gastroenteritis(BICE).Methods:Infants with mild gastroenteritis accompanied with seizures were observed and followed up from November 2001 to October 2006.Results:The ages of onset in 31 cases with mild gastroenteritis accompanied with BICE ranged from 5 to 25 months old,and the prevailing age was between 12 and 24 months old(22 cases).All episodes occurred in winter.The average number of seizures during a single episode was 1.4.The seizure occurred as generalized tonic-clonic pattern.During interval,only one infant presented as active 4-5 Hz θ-wave on electroencephalogram.The brain imaging blood biochemical profile and cerebrospinal fluid testing did not show abnormality in all cases.No antiepileptic medications were prescribed to the patients as the seizures had stopped.One infant experienced relapses that did not happen more than twice.The course of BICE lasted less than one year.All cases demonstrated normal psychomotor development and had no family history of febrile convulsion of epilepsy.Conclusions:The infantile seizures could be associated with mild gastroenteritis,and occur in cases,presenting as temporal episode.The special treatment is not necessary and the prognosis is good.更多还原