【摘要】 目的:探讨血清HBV DNA水平与HBV标志物(HBVM)表现模式、肝损害程度的关系。方法:采用荧光定量PCR分析系统检测126例乙肝病毒感染者HBV DNA,采用ELISA法检测HBVM。结果:在HBsAg阳性+HBeAg阳性+抗HBc阳性的血清中HBV DNA阳性率和含量最高,血清HBeAg与HBV DNA含量有一定关系(P<0.01),血清丙氨酸氨基转移酶水平与HBV DNA含量亦有一定关系(P<0.05)。结论:HBV DNA含量与HBeAg有一定关系,肝脏损害程度与血清HBV DNA亦有一定关系。更多还原

【Abstract】 Objective:To explore the relation between the nucleic acid content of hepatitis B virus(HBV)and HBV markers,liver injury.Methods:One hundred and twenty-six patients suffering from hepatitis B received HBV DNA analysis.Fluorescence ration PCR analysis was performed for HBV DNA quantifying assessment.HBV markers were detected by ELISA.Results:Serum HBeAg was related to HBV DNA(P<0.01).The highest HBV DNA levels were presented in sera positive for both HBsAg and HbeAg(P<0.05).Serum alanine amjnotransferase level and HBV DNA content were correlated.Conclusions:The quantity of HBV DNA is related to HbeAg.Liver injury stage is related to serum HBV DNA content.更多还原