【摘要】 目的:建立复方柏芍胶囊的质量标准。方法:采用薄层色谱法对制剂中黄柏、赤芍、丹参进行定性鉴别,采用高效液相色谱法对主药成分盐酸小檗碱进行含量测定。结果:薄层色谱法可鉴别出黄柏、赤芍、丹参,盐酸小檗碱在2.43~58.32μg范围内呈良好的线性关系,r=0.999 5,平均回收率为99.3%,RSD为1.88%。结论:薄层色谱法与高效液相色谱法简便、快捷、重现性好,可用于复方柏芍胶囊的质量控制。更多还原

【Abstract】 Objective:To establish the quality standard for Fufang Boshao Capsule.Methods: Cortex phellodendri,Radix rubra paeoniae and Radix salviae miltiorrhiae were qualitatively identified by TLC.Berberine chloride was determined by HPLC.Results:TLC could be used to identify Phellodendron chinensis cortex,Paeoniae rubra radix,Sollviae miltiorrhizae radix et rhizoma.Berberine chloride had a linear relation with peak area in the range of 2.43~58.32 μg(r=0.999 5).The average recovery was 99.3%(RSD=1.88%) in berberine chloride.Conclusion:The established methods are simple,quick and reproduciable,which could be used for the quality control of Fufang Boshao Capsule.更多还原