【摘要】 目的:观察纯中药制剂丹蛭降糖胶囊对2型糖尿病患者B细胞功能的影响,探讨中医药在治疗2型糖尿病及延缓其进程中的作用。方法:62例2型糖尿病患者随机分成两组,治疗组32例服用丹蛭降糖胶囊,对照组30例服用马来酸罗格列酮,疗程为2个月,以胰岛素敏感指数及Ho-ma模型公式评估各组B细胞功能。结果:两组中医证候积分及B细胞功能均有改善,且治疗组明显优于对照组(P<0.05,P<0.01)。结论:丹蛭降糖胶囊具有降低血糖,改善高胰岛素血症,提高2型糖尿病患者胰岛素敏感性,改善胰岛素抵抗的作用。更多还原

【Abstract】 Objective:To observe the effects of Danzhi Jiangtang Capsule on B-cell function of pancreatic islet in patients with type 2 diabetes,and explore its contribution to treating and delaying the development of type 2 diabetes.Methods:Sixty-two patients were randomly divided into treatment group(n=32) and control group(n=30).Treatment group was treated with Danzhi Jiangtang Capsules,while control group with rosiglitazone for two months.The scores of traditional Chinese medicine syndrome,ISI and Homa-B were calculated before and after the therapy.Results:Comparing with those of control group,the above indexs of treatment group were significantly improved(P<0.05,P<0.01).Conclusion:Danzhi Jiangtang Capsule could reduce blood glucose,enhance insulin sensibility and improve the patients′ hyperinsulinemia and insulin resistence.更多还原