【摘要】 以丙酮为光敏剂,用300 W高压紫外汞灯辐照N,N-二甲基胸腺嘧啶,合成N,N-二甲基胸腺嘧啶二聚体,经过1H NMR、13CNMR、MS和X-射线衍射确定了产物结构是cis-syn构型。无溶剂直接光照这种方法将二聚体还原成单体,避免了使用溶剂而造成的污染,且提高了嘧啶二聚体的效率。更多还原

【Abstract】 N,N-Dimethylthymine Dimer(DMTD) was synthesized under 300 W ultraviolet mercury lamp with acetone as photosensitizer and DMT as the resource.Its configuration(cis-syn) was obtained by 1H NMR,13C NMR,MS and X-ray diffraction.The method of irradiation with solvent free condition could reduce DMTD to DMT,which avoided the pollution of using solvent and improved DMTD efficiency.更多还原