【摘要】 目的观察激光周边虹膜成形术对非瞳孔阻滞型房角关闭的治疗效果。方法病例系列研究:对17例(31只眼)非瞳孔阻滞型原发性闭角型青光眼(PACG)于周边虹膜切除术后进行激光周边虹膜成形术治疗,采用超声生物显微镜于术前和术后1周测量房角宽度和虹膜厚度,并应用前房角镜观察房角粘连情况。随访3～17月,平均8月。结果激光周边虹膜成形术后一周,房角开放距离(AOD)较术前明显增大(P<0.01),小梁虹膜夹角(TIA)增宽、部分患者周边虹膜前粘连(PAS)减少、周边虹膜变薄,随诊期间未发现高眼压及前房角进行性粘连。结论激光虹膜成形术可以明显加深非瞳孔阻滞型PACG的周边前房,增宽房角入口,从而预防房角粘连的进一步进展。更多还原

【Abstract】 Objective To investigate the efficacy of laser iridoplasty in non-pupillary blockage ofangle closure. Methods Case series reports. Thirty one eyes in 17 patients were confirmed to be non-pupillaryblockage of angle with ultrasound biomicroscope (UBM) after iridotomy. Laser iridoplasty was performed in allthese eyes. Before and one week after iridoplasty, we measured the anterior chamber depth, width of angle, iristhickness with UBM. Dynamic gonioscopy was used to evaluate the progression of peripheral anterior synechia(PAS). All the patients were follow-up from 3 months to 17 months. Results Angle open distance (AOD) afteriridoplasty was increased (p<0.01). Trabecular-iris angle (TIA) was widen (p<0.01) and the extents of PAS werereduced in some cases. During the period of follow-up, no acute increase of IOP and progression of PAS werefound. However, AOD and TIA were reduced quantitatively, although not significantly. Conclusions Laseriridoplasty can deepen peripheral anterior chamber and increase the angle access of eyes with non-pupillaryblockage or multiple-mechanism angle-closure, therefore it can prevent the angle-closure from progressing.However, the long-term course needed to be confirmed.更多还原