【摘要】 目的观察经瞳孔温热疗法(transpupillarythermotherapy,TTT)治疗息肉状脉络膜血科病变(phlypoidalchoroidalvasculopathy)的临床疗效。方法经荧光血管造影(FFA)、吲哚菁脉络膜血管造影(ICGA)和光相干断层成像术(OCT)检查确诊的16例19眼PCV患者,进行TTT治疗,患者年龄43岁～76岁,平均59.4岁,男10例11眼,女6例8眼,有4眼行两次治疗,有1眼行3次治疗。有5眼为玻璃体出血玻璃体切割术后,有2眼联合PDT治疗。术前和术后均行视力,眼底检查,彩色眼底像,荧光血管造影(FFA)和吲哚菁绿脉络膜血管造影(ICGA),光学相干断层成像术(OCT)检查,随诊3m～24m。结果TTT治疗后视力提高2行以上4眼(21.1%),视力不变15眼(78.9%)。TTT治疗后ICGA显示息肉状脉络膜血管扩张减少和消失16眼(84.2%),1(5.3%)眼扩大,2眼(10.5%)在别处复发,未见明显的并发症。结论TTT治疗息肉状脉络膜血管病变是有效和安全的,可稳定病变的进展及患者的视力,需要更多的病例和更长的随诊时间来验证。更多还原

【Abstract】 Objective To study clinical results of transpupillary thermotheraphy (TTT) for patients with polypoidal choroidal vasculopathy (PCV). Methods Sixteen cases (19 eyes) with polyoidal choroidal vasculopathy diagnosed by fluorescein angiography (FFA), indocyanine green angiography (ICGA) and optic coherence tomography (OCT) were treated with TTT. The average age of this group was 59.4. Ten cases (11 eyes) were male. Six cases (8 eyes) were female. There were four eyes for two times treatment and one eye for three times. Visual acuity, FFA, ICGA and OCT were evaluate before and after treatment. The follow-up was 3- 24 months. Results After TTT, The visual acuity of four eyes (21.1%) were increased at least 2 lines. The visual acuity of 15 eyes (78.9%) were stable. After TTT, ICGA showed that polypoidal structure of 16 eyes (84. 2%) was disappeared or reduced, 1 eye (5.3%) was enlarged, 2 eyes (10.5%) was recured in other place. Con- clusions TTT for polypoidal choroidal vasculopathy is safe and effective. TTT can make this disease stable. We need more cases and longer follow-up to evaluate this kind of treatment.更多还原