【摘要】 目的观察舒肺颗粒对慢性肺源性心脏病右心功能不全的治疗效果。方法将100例患者按抽签法随机分为两组。对照组(40例)采用氟罗沙星0.2g静脉滴注,每天2次;喘定,每次0.2g,每天3次口服;治疗组(60例)在对照组治疗基础上加用舒肺颗粒10g,每天3次口服;两组疗程均为3周,并观察心功能、右心功能(A峰、E峰、VA/VE、SPAP、PEP、RVET、PEP/RVET)、临床症状、体征、舌象的改善情况,血气分析指标的变化。结果总有效率治疗组(91.7%)明显优于对照组(70.0%,P<0.01);中医症状积分、心功能和实验室指标等方面,治疗组均优于对照组,两组比较差异有显著性(P<0.05,P<0.01)。结论舒肺颗粒是治疗慢性肺源性心脏病右心功能的有效药物。更多还原

【Abstract】 ObjectiveTo observe the effect of Shufei Granule (SG) on right ventricular function in patients with chronic pulmonary heart disease (CPHD). MethodsOne hundred CPHD patients were randomly divided into two groups, the control group (n=40) treated with fleroxacin 0.2 g twice per day by intravenous dripping and diprophylline 0.2 g 3 times per day orally, the treatment group (n=60) treated with SG 10 g 3 times a day orally additionally besides the treatment given to the control group. The therapeutic course for both groups was 3 weeks. The changes of the cardiac function, the right ventricular function 〔A peak velocity (VA), E peak velocity (VE), VA/VE, systolic pulmonary artery pressure (SPAP), pre-ejection period (PEP), right ventricular ejection time (RVET), PEP/RVET〕, and blood-gas analysis were investigated, the condition of clinical symptoms and signs as well as tongue pictures were observed also. ResultsThe total effective rate was 91.6% in the treated group, significantly higher than that in the control group (70.0%, P<0.01); the improvements in symptom score, cardiac function and the other laboratory indexes were all superior in the treatment group to those in the control group (P<0.05,P<0.01). ConclusionSG is an effective drug for improving right ventricular function in CPHD patients.更多还原