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自然流产妇女血清氧化应激状态分析

An analysis of oxidative stress in serum of pregnant women with abortion.

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【作者】 马秀菊肖文霞

【Author】 MA Xiu-ju,XIAO Wen-xia.(Department of Gynecology and Obstetrics.The Second Hospital of HeBei Medical University,Hebei Shijiazhuang 050000,China)

【机构】 河北医科大学第二医院妇产科河北医科大学第二医院妇产科 河北石家庄050000河北石家庄050000

【摘要】 目的通过对自然流产女妇血清氧化应激指标———超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(VE)的测定,分析其氧化应激状态。方法用化学比色法对20例正常未孕妇女、20例正常孕早期妇女及20例自然流产妇女血清中SOD、MDA及VE进行测定。结果与未孕妇女相比,正常孕早期妇女血清MDA升高(P<0.05),SOD和VE也显著升高(P<0.05;P<0.05);与正常孕早期妇女相比。自然流产妇女血清MDA水平升高(P<0.05),SOD、VE水平却下降(P<0.05;P<0.05)。结论自然流产妇女处于氧化应澈状态中。

【Abstract】 Objective:To determine the levels of maternal serum SOD,MDA and VE in patients with abortion in order to analyze their oxidative stress.Methods:The levels of maternal serum SOD,MDA and VE were measured in 20 healthy non-pregnant women,20 normal early pregnant women and 20 patients with abotrion by chemocoiorimetry.Results:The levels of maternal serum MDA in normal early pregnant Women were significantly higher than those of non-pregnant women(P<0.05),so were the levels of SOD and VE(P<0.05,P<0.05);the levels of maternal serum MDA in patients with abortion were also higher than those of normal early pregnant women(P<0.05),while the levels of SOD and VE were significantly decreased(P<0.05,P<0.05).Conclusion:The pregnant women with abortion were in oxidative stress.

  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2006年05期
  • 【分类号】R714.21
  • 【被引频次】3
  • 【下载频次】75
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