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自然流产妇女血清氧化应激状态分析
An analysis of oxidative stress in serum of pregnant women with abortion.
【摘要】 目的通过对自然流产女妇血清氧化应激指标———超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(VE)的测定,分析其氧化应激状态。方法用化学比色法对20例正常未孕妇女、20例正常孕早期妇女及20例自然流产妇女血清中SOD、MDA及VE进行测定。结果与未孕妇女相比,正常孕早期妇女血清MDA升高(P<0.05),SOD和VE也显著升高(P<0.05;P<0.05);与正常孕早期妇女相比。自然流产妇女血清MDA水平升高(P<0.05),SOD、VE水平却下降(P<0.05;P<0.05)。结论自然流产妇女处于氧化应澈状态中。
【Abstract】 Objective:To determine the levels of maternal serum SOD,MDA and VE in patients with abortion in order to analyze their oxidative stress.Methods:The levels of maternal serum SOD,MDA and VE were measured in 20 healthy non-pregnant women,20 normal early pregnant women and 20 patients with abotrion by chemocoiorimetry.Results:The levels of maternal serum MDA in normal early pregnant Women were significantly higher than those of non-pregnant women(P<0.05),so were the levels of SOD and VE(P<0.05,P<0.05);the levels of maternal serum MDA in patients with abortion were also higher than those of normal early pregnant women(P<0.05),while the levels of SOD and VE were significantly decreased(P<0.05,P<0.05).Conclusion:The pregnant women with abortion were in oxidative stress.
【Key words】 Oxidative stress; Abortion; Superoxide dismutase; Malondialdehyde; Vitamin E;
- 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2006年05期
- 【分类号】R714.21
- 【被引频次】3
- 【下载频次】75