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氧化应激与胎膜早破的相关性研究

The study of relationship between oxidative stress and premature rupture of membranes.

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【作者】 马秀菊肖文霞

【Author】 MA Xiu-ju,XIAO Wen-xia.(Department of Gynecology and Obstetrics,The Second Hospital of Hebei Medical University,Hebei Shijiazhuang 050000,China)

【机构】 河北医科大学第二医院妇产科河北医科大学第二医院妇产科 河北石家庄050000河北石家庄050000

【摘要】 目的通过对胎膜早破孕妇蜕膜和血清中氧化应激指标—超氧化物歧化酶(SOD)、丙二醛(MDA)及维生素E(VE)的测定,探讨氧化应激与胎膜早破的关系。方法用化学比色法对30例胎膜早破孕妇和30例正常孕足月妇女蜕膜和血清中SOD、MDA及VE进行测定。结果与正常孕足月妇女相比,胎膜早破孕妇蜕膜和血清中MDA水平都升高(P<0.05),SOD、VE水平却都下降(P<0.05,P<0.05)。结论氧化应激与胎膜早破具有相关性。

【Abstract】 Objective: To determine the levels of SOD,MDA and VE in decidua and maternal serum of patients with premature rupture of membranes to clarify relationship between oxidative stress and premature rupture of membranes.Methods: The levels of SOD,MDA and VE in decidua and maternal serum were measured in 30 patients with premature rupture of membranes and 30 term-pregnant women by chemocolorimetry.Results: The levels of MDA in decidua and maternal serum of patients with premature rupture of membranes were significantly higher than those of term-pregnant women(P<0.05),while the levels of SOD and VE were significantly decreased(P<0.05,P<0.05).Conclusion: Oxidative stress is associated with premature rupture of membranes.

  • 【文献出处】 中国优生与遗传杂志 ,Chinese Journal of Birth Health & Heredity , 编辑部邮箱 ,2006年01期
  • 【分类号】R714.433
  • 【被引频次】20
  • 【下载频次】76
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