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中药结肠透析治疗慢性重型肝炎的临床研究
The Study on the Effects of Colon Herbal Dialysis in Patients with Chronic Severe Hepatitis B
【摘要】 目的:观察中药结肠透析疗法对慢性重型肝炎的临床效果。方法:60例慢性重型肝炎患者按分层随机配对分为观察组和对照组各30例,对照组给予常规护肝、降酶、退黄以及补充白蛋白等支持治疗,观察组在基础上加用HC-3000结肠途径治疗机透析治疗,每次先用结肠灌洗液间歇灌洗60m in,深度50 cm,然后注入由大黄、石菖蒲、莱菔子、蒲公英、牡蛎、水牛角等组成的中药结肠透析液100~200mL,保留灌肠1~2h,每周2次,连续4周后观察患者主要症状、体征及并发症的改善情况,同时检测治疗前后肝功能(TB il、ALT、ALB、CHE)、凝血酶原时间(PT)和血氨(NH3)等指标。结果:观察组临床总有效率76.66%,对照组53.33%,观察组明显优于对照组,P<0.05;观察组中TB il、ALT、ALB、CHE、PT和NH3等指标的改善也明显优于对照组,P<0.01。结论:中药结肠透析配合综合支持治疗慢性重型肝炎疗效显著。
【Abstract】 Objective: To investigate the effects of colon herbal dialysis in patients with chronic severe hepatitis B.Methods:60 cases of chronic severe hepatitis were divided into observe group and control group randomly,30 cases in respectively.Control group was treated with routine approaches comprised of liver protecting,kata-ALT,detoxicating and albumin supplementing,et al,at the same time,adding colon herbs dialysis to the cases of observe group with HC-3000 therapeutic machine.At first,intermittence lavage using coloclysis solution at the depth of 50cm,60min,then infund 100~200ml herbs colon dialysis solution constituted by rhubarb,acori graminei,semen raphani,dandelion, oyster and cornu bubali,et al,remaining 1~2h,biw,continuous4wks.Observe the amelioration of primary symptoms,physical signs and complications in all of the cases,as well as the change of liver function,prothrombin time and the contents of blood ammonia.Results: The total effective rate of the cases in observe group was 76.66%,better than the rate of control group(53.33%)significantly,P<0.05,the effects on bilirubin,albumin,prothrombin time and the contents of blood ammonia were statistic difference also.Conclusions:The effects of colon herbal dialysis combining with supportive treatment on chronic severe hepatitis are significant.
- 【文献出处】 中医药学刊 ,Chinese Archives of Traditional Chinese Medicine , 编辑部邮箱 ,2006年07期
- 【分类号】R259.126
- 【被引频次】30
- 【下载频次】113