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“Ⅰ+Ⅱ”疗法对高血压肥胖大鼠血浆神经肽Y含量的影响

The Effect of "Ⅰ+Ⅱ"Therapeutics on Plasma Neuropeptide Tytosine in Obese Rats with Hypertension

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【作者】 杨雨民程志清

【Author】 YANG Yu-min,CHENG Zhi-qing (zhejiang college of TCM,hangzhou 310053,Zhejiang,China)

【机构】 浙江中医学院浙江中医学院 浙江杭州310053浙江杭州310053

【摘要】 目的:观察“Ⅰ+Ⅱ”疗法对高血压肥胖大鼠神经肽Y(NPY)水平的影响。方法:以营养饲料饲养自发性高血压大鼠(SHR)照模成高血压肥胖大鼠,观察“Ⅰ+Ⅱ”疗法治疗前后高血压肥胖大鼠血压、体重、身长和血浆NPY水平,并与基础治疗、中药治疗和针灸治疗进行比较。结果:经“Ⅰ+Ⅱ”疗法治疗30天后,高血压肥胖大鼠血压、体重、lee’s指数和NPY水平有所下降。结论:“Ⅰ+Ⅱ”疗法具有减肥降压作用。

【Abstract】 Objective:To observe the effect of "Ⅰ+Ⅱ"therapeuticson the level of plasma neuropepride tytosine(NPY)in obese ratswith hypertension.Methods:The model of obese rat with hypertension was established by feeding the Spontaneously Hypertensive Rat(SHR)with high fat diet.Before and after "Ⅰ+Ⅱ"therapeuticstreatment,we observed the blood pressure,body weight,Lee’s index and the level of plasma NPYof obese rat with hypertension,and contrasted with those of groups of basic therapy,needle therapyandChinese Traditional Medicine.Results: After thirty days treatment of "Ⅰ+Ⅱ"therapy,The blood pressure,body weight,Lee’s index and the level of plasma NPY ofobese rat with hypertension were significantly reduced.Conclusion: "Ⅰ+Ⅱ"therapeuticshave the effects of reducingweightand depressing blood pressure.

【基金】 浙江省卫生厅科技专项基金资助(2003zc039)
  • 【文献出处】 中医药学刊 ,Chinese Archives of Traditional Chinese Medicine , 编辑部邮箱 ,2006年02期
  • 【分类号】R259
  • 【被引频次】2
  • 【下载频次】128
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