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三七总皂苷提取工艺研究
Studies on Extraction Process Optimization of Panax notogingseng Saponins
【摘要】 目的:优化三七总皂苷提取工艺。方法:在考察提取溶媒和粒径的前提下,采用正交试验法,以提取物中三七总皂苷含量为考察指标,对影响三七提取的因素进行了考察。结果:提取次数对三七总皂苷得率有显著影响。选择过8目筛的药材,用10倍量70%乙醇提取3次,每次1.5h,所得三七总皂苷为85.74±3.16mg/g生药。结论:该工艺简便易行,得率较高,适于大生产。
【Abstract】 Objective: To optimize the conditions for the extraction of panax notogingseng saponins (PNS). Methods: After selected extraction solvent and suitable particle, we employed orthogonal experimental design to examine the conditions for the extraction by determination of PNS. Results: Significant effect was observed only in extraction times. Conclusion: The optimum condition for extraction of PNS was to extract panax notogingseng (Burk.) F. H. Chen with 10 times 70% ethanol for 1.5 hours for 3 times.
【关键词】 三七总皂苷;
三七;
提取工艺;
正交试验;
【Key words】 Panax notogingseng Saponins; Panax notogingseng (Burk. ) F. H. Chen; Extraction process; Orthogonal experiment;
【Key words】 Panax notogingseng Saponins; Panax notogingseng (Burk. ) F. H. Chen; Extraction process; Orthogonal experiment;
【基金】 浙江省中医药管理局重点资助项目(No.2003KF001);浙江省科技厅计划重点资助项目(No.2004C33106)
- 【文献出处】 中药材 ,Journal of Chinese Medicinal Materials , 编辑部邮箱 ,2006年06期
- 【分类号】TQ461
- 【被引频次】45
- 【下载频次】2615