【摘要】 目的:建立复方苦参肠炎康胶囊中苦参碱的含量测定方法。方法:采用HPLC法,Hypersil NH2柱(250 mm×4．6 mm,5μm),乙腈-无水乙醇-0．1 mol·L-1磷酸溶液(93:3．5:3．5)为流动相,检测波长为205 nm。结果:苦参碱在0．16～0．80μg呈良好的线性关系(r=0．999 6);苦参碱平均回收率为97．26％,RSD为2．1％。结论:该方法简便准确,重现性好,可用于复方苦参肠炎康胶囊的质量控制。更多还原

【Abstract】 Objective: To establish a HPLC method for quantification of matrine in compound capsules of Sophorae flavescentis for relieving enteritis ( Fufang Kushen Changyankang Capsules ) . Methods: The HPLC condition was consisted of a Hypersil NH2 column(250 mm×4.6 mm,5μm) , a mobile phase of acetonitrile-ethanol-0.1 mol·L-1 H3PO4(93:3. 5:3. 5)and a detection wavelength at 205 nm. Results:The linearity of matrine concentration curve was in a range of 0. 16 - 0. 80μg( r = 0. 999 6). The average recovery of matrine was 97. 26% ( RSD =2. 1% ). Conclusion: The HPLC method is used for the quality control of Fufang Kushen Changyankang Capsules.更多还原