【摘要】 目的:探讨大黄对脓毒症患者凝血功能的影响。方法:将30例无凝血功能障碍的脓毒症患者随机分为两组,对照组15例给予常规综合治疗,治疗组15例加用大黄10 g鼻饲。分别检测两组患者治疗前及治疗后1、3和7 d的凝血酶原时间(PT)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FBG)和血小板(PLT)计数。结果:两组治疗后PT、TT、APTT均延长,FBG和PLT下降。治疗组治疗后第7日PT、TT、APTT均显著升高,FBG和PLT均显著降低,与对照组比较差异均有显著性(P均<0.05)。结论:大黄对脓毒症患者的凝血功能有保护作用。更多还原

【Abstract】 Objective: To investigate the effect of rhubarb on blood coagulation in patients with sepsis.Methods: Thirty septic patients with normal blood coagulation were randomly divided into two groups:(treatment) group and control group.Both groups were treated with routine integration treatment,and(additionally),the treatment group was treated with rhubarb via nasal tube.Prothrombir time(PT),thrombin time(TT),activated partial thromboplastin time(APTT),fibrinogen(FRG) and platelet count(PLT) were detected before and 1,3,7 days after treatment in the two groups.Results: At 7 days after treatment in the treatment group,PT,TT and APTT all increased,while both FBG and PLT decreased compared to those of the control group(all P<0.05).Conclusion: Rhubarb has a protection effect on blood coagulation in patients with sepsis.更多还原