【摘要】 目的:探讨视网膜母细胞瘤的CT表现与病理诊断的关系及其诊断、鉴别诊断价值。方法:回顾性分析49例经手术病理证实的视网膜母细胞瘤的临床资料、CT表现及病理结果,并进行对照研究。结果:49例眼眶CT检查均显示为眼球内高密度软组织肿块,密度均匀27例,不均匀22例,眼球内钙化45例(91.8%),眼球增大11例,视神经增粗8例,病变侵犯眶内6例、颅内2例。病理分型:未分化型28例,分化型21例。镜下见肿瘤细胞排列成菊花状或假菊花状,绝大部分肿瘤内可见钙化,部分肿瘤细胞出现变性、坏死。两型的CT表现在肿块密度上有显著性差异(P<0.01)。CT定性诊断准确率95.9%(47/49例)。结论:CT可以显示肿瘤的形态、大小、内部特征及其累及范围,对定性诊断具有重要意义。更多还原

【Abstract】 Objective:To investigate the relationship between CT findings and pathologic diagnosis of retinoblastoma and their value in diagnosis and differentiation.Methods:The clinical data,CT findings and pathologic results of 49 cases of retinoblastoma which proved by operation and pathology were analyzed retrospectively and comparatively.Results:49 cases of orbit CT examination showed high density of soft tissue mass in the globe,homogeneous density in 27 cases,non-homogeneous density in 22 cases,45 cases(91.8%) of calcification in globe,enlargement of globe in 11 cases,enlargement of optic nerve in 8 cases,2 cases of intracranial invasion and 6 cases of intra-orbit.Pathological typing undifferentiated type 28 cases,differentiated type 21 cases,the tumor cells arranged like chrysanthemum or pseudo chrysanthemum in form in microscope,most of the tumors contained calcification,apart of tumor appealed degeneration and necrosis.The density of mass in CT findings of two type had major difference(P<0.01).The rate of accuracy in qualitative diagnosis of CT was 95.5%(47/49 cases).Conclusion:CT can show the size,shapes,internal features and invasive degree of the lesion,it has an important value in qualitative diagnosis.更多还原