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吸入全麻和吸入全麻联合硬膜外麻醉对胃癌根治术患者清醒时MAC的影响
Comparison of Effects of General Anesthesia and Combined General-Epidural Anesthesia on MAC-Awake of Isoflurane in Patients Undergoing Gastrectomy
【摘要】 目的:比较吸入全麻和吸入全麻联合硬膜外麻醉对术后清醒时M AC和S tew ard苏醒评分的影响。方法:30例择期行胃癌根治术的患者,随机分成两组:吸入全麻组(全麻组)和吸入全麻联合硬膜外麻醉组(联合组),每组15例。联合组硬膜外给予1.6%利多卡因12~14 m l,两组均采用异丙酚2 m g/kg和琥珀胆碱1.5 m g/kg诱导插管,用维库溴铵、异氟醚维持麻醉,两组异氟醚用量相同。手术结束时快速洗出体内异氟醚,进行S tew ard苏醒评分。结果:全麻组清醒M AC为(0.40±0.06)%,S tew ard苏醒评分4.10±0.04;联合组清醒M AC为(0.25±0.05)%,S tew ard苏醒评分为4.70±0.05。结论:吸入麻醉联合硬膜外麻醉术后清醒时M AC降低,S tew ard苏醒评分高。
【Abstract】 Objective:To determine the awakening concentration of isoflurane and evaluate the emergence from anesthesia in the presence and absence of epidural block.Methods:Thirty patients aged 45~65 years undergoing elective radical gastrectomy were randomly divided into general anesthesia group(GA,n=15) and combined general-epidural anesthesia group(CGEA,n=15).In CGEA group epidural block was given a dose of 12~14 ml of 1.6% lidocaine.General anesthesia was induced with propofol 2.0 mg/kg and succinylcholine 1.5 mg/kg.Anesthesia was maintained with similar concentration of isoflurane in two group.At the end of operation isoflurane was washed out quickly.The end-tidal isoflurane concentration was recorded as MAC-awake and Steward score was evaluated.Results:MAC-awake of isoflurane was 0.4% in GA group and 0.25% in CGEA group.Steward score was 4.1 in GA group and 4.7 in CGEA group.Conclusion:Epidural block with lidocaine reduces the MAC-awake.Steward score is higher in CGEA group than that in GA group.
【Key words】 Anesthesia,inhalation; Anesthesia,epidural; Stomach neoplasms/surgery; Anesthesia recovery period;
- 【文献出处】 中国误诊学杂志 ,Chinese Journal of Misdiagnostics , 编辑部邮箱 ,2006年18期
- 【分类号】R614
- 【被引频次】4
- 【下载频次】54