【摘要】 目的探讨经皮微波热凝固(percutaneous m icrowave coagu lation therapy,PMCT)治疗周围型肺癌的临床疗效、影像学变化及不良反应。方法2003年8月~2004年10月我们在CT引导下PMCT治疗周围型肺癌16例(鳞癌9例,腺癌7例)。经皮肺穿刺将针式微波天线穿刺到肿瘤内,以2 450 MHz的微波、功率为65~75 W每点加热3~5 m in,根据肿瘤大小、形状选择1点或多点加热。结果手术时间15~60 m in,平均35 m in。术后3例发生气胸,6例发生少量胸腔积液。CR 1例,PR 4例,NC 11例。16例随访3~15个月,平均9.5个月,肿瘤转移2例,死亡1例。结论PMCT治疗周围型肺癌对不能耐良开胸手术的病人是一种有一定疗效、微创、安全的新方法。更多还原

【Abstract】 Objective To evaluate the clinical effects,CT features and side-effects of percutaneous microwave coagulation therapy(PMCT) in the treatment of peripheral lung cancer.Methods CT-guided PMCT was applied to 16 cases of peripheral lung cancer from August 2003 to October 2004 in this hospital.Pathological or cytological findings showed 9 cases of squamous carcinoma and 7 cases of adenocarcinoma.A needle microwave antenna was applied into the tumor percutaneously under CT guidance.In each emission of microwave,the tumor was ablated with a 2 450 Hz microwave coagulation output of 65~75 W for 3~5 min.According to the size and shape of the tumor,single or multiple ablation emission was selected.Results The operation time was(15~60) min(mean,35 min).Complete remission(CR) was achieved in 1 case,partial remission(PR) in 4 cases,and no changes(NC) in 11.Follow-up observations in the 16 cases for 3~15 months(mean,9.5 months) found 2 cases of tumor metastasis and 1 case of death.Conclusions Percutaneous microwave coagulation therapy is a safe,micro-invasive,and effective treatment for the management of peripheral lung cancer.更多还原