【摘要】 目的探讨血浆同型半胱氨酸水平与皮质下动脉硬化性脑病(Binswanger病)的关系。方法随机选取Binswanger病患者30例作为病例组和同期在我院进行体检的30例健康老年人作为对照组,应用高效液相色谱法测定两组研究对象的血浆总同型半胱氨酸(tHcy)水平。结果病例组患者血浆tHcy水平为(21．05±12．89)μmol/L,正常对照组为(11．58±5．25)μmoL/L,两组间差别有显著性意义(P＜0．001)。结论皮质下动脉硬化性脑病患者血浆tHcy明显升高,高同型半胱氨酸血症可能是皮质下动脉硬化性脑病的危险因素之一。更多还原

【Abstract】 Objective To explore the relationship between plasma homocysteine level and Binswanger’s disease (BD).Methods 30 BD patients and 30 normal subjects were enrolled in the study.Their plasma total homocysteine (tHcy) level were measured with high performance liquid chromatography.Results Mean plasma tHcy levels was higher in BD patients than in control group (P＜0.01).Conclusion It reveals that the increasing plasma tHcy may play an important role in BD. Hyperhomocysteinemia may be a dangerous factor of BD.更多还原