【摘要】 目的探讨下肢骨折病人D二聚体定量检测的临床价值。方法采用增强型乳胶免疫比浊法对109例下肢骨折患者术前、术后第3天及术后第7天进行血浆D二聚体的定量检测,跟踪观察患者病情。结果109例患者有10例并发DVT,并发DVT组术前、术后第3天及术后第7天血浆D二聚体的检测结果有显著性差异(P<0.05),呈进行性增高。未并发DVT组术前、术后第3天及术后第7天血浆D二聚体的检测结果无显著性差异(P>0.05)。而并发DVT组与未并发DVT组相比较:术前血浆D二聚体的检测结果无显著性差异(P>0.05);术后第3天血浆D二聚体的检测结果有显著性差异(P<0.05);术后第7天血浆D二聚体的检测结果有显著性差异(P<0.01)。结论血浆D二聚体的动态监测对骨折术后并发血栓性疾病具有早期诊断价值。更多还原

【Abstract】 Objective The aim of this study was to evaluate the measurement of plasma D-dimer level in lower limbs fracture.Methods Automated latex immunoassay for the determination was used to detect plasma D-dimer in 109 patients with lower limbs fracture during the phases preoperative,3 days and 7 days postoperative.[WTHZ]Results 10 patients occur deep vein thrombosis (DVT). The different level of D-dimer during the phases preoperative,3 days and 7 days postoperative in DVT group was significant(P< 0.05).The different level of D-dimer during the phases preoperative,3 days and 7 days postoperative in NO DVT group was not significant(P> 0.05).The different level of D-dimer between two groups: preoperative was not significant(P>0.05),3 days postoperative was significant(P<0.05).7 days postoperative was significant(P<0.01).Conclusion Automated latex immunoassay for the determination of D-dimer is very useful for predicting occurrence of thromboembolism in lower limbs fracture.更多还原