【摘要】 目的探讨老年心脑血管疾病患者血清铁蛋白(SF)和β2-微球蛋白(β2-GM)测定的临床价值。方法用电化学发光法和免疫比浊法分别对60岁以上的56例冠心病、75例高血压、38例脑梗死患者的血清测定SF、β2-GM,并同时测定尿素氮(Urea)和肌酐(Cr),与正常健康对照组进行对比。结果老年冠心病、高血压、脑梗死患者血清SF、β2-GM的含量均明显高于健康对照组,有显著性差异(P<0.01)。结论SF、β2-GM参与了老年心脑血管疾病的病理生理过程,为老年心脑血管疾病的诊断、治疗和判断预后提供了参考指标。另外β2-GM为老年心脑血管疾病早期肾损伤的敏感指标。更多还原

【Abstract】 Objective To discuss the Clinical Significance of measuring SF and β₂-GM in old patients with cardiovascular and cerebrovascular diseases and their clinical significance.Methods Using ECLIA and Immunoturbidimetric methods to measure the serum levels of SF and β₂-GM in 56 old patients with coronary cardiopathy 、75 old patients with hypertension、38 old patients with cerebral infarction and 80 healthy controls and measuring Urea and Cr as well.Results The the levels of SF and β₂-GM in old patients with cardiovascular and cerebrovascular diseases were higher than those of controls（P<0.01）.Conclusion SF andβ₂-GM may take a part in the pathogenesis of cardiovascular and cerebrovascular diseases,so that they may be used as references to therapeutic effectiveness and prognosis.更多还原