【摘要】 目的:研究家兔红细胞阻抗谱并建立RC等效电路模型参数。方法:在0.01MHz~100MHz频率范围,使用Agilent 4294A阻抗分析仪测量了家兔红细胞交流阻抗,通过Bode图、Nyquist图、Nicols图、Randles图的曲线拟合分析,比较三个RC等效电路模型的拟合残差。结果:(1)家兔红细胞阻抗谱的第一特征频率fc1=2.5MHz,第二特征频率fc2=5.25MHz;(2)等效电路模型,模型3的拟合误差小于模型1和模型2;(3)等效的单个红细胞膜电容约为0.458μF/cm2。结论:家兔红细胞阻抗谱表现出两个特征频率,其等效电路模型以模型3形式更为合理。更多还原

【Abstract】 Objective:To study impedance spectra of rabbit erythrocytes,and establish its equivalent circuit model parameters.Method:The AC impedance of rabbit erythrocytes have been measured with the Agilent 4294A impedance analyzer at frequency range of 0.01MHz～100MHz,then curve fitting residual error of rabbit erythrocyte’s equivalent circuit have been compared by the Bode plot,the Nyquist plot,the Nicols plot and the Randles plot.Results:1)The characteristic 1^st frequency（f-（c1）） was 2.5MHz,the characteristic 2^nd frequency（f-（c2）） was 5.25MHz for impedance spectra of rabbit erythrocytes;2)Curve fitting residual error of equivalent circuit of model-3 was less than those of model-1 and model-2;3)The membrane capacitance of equivalent single erythrocyte was about 0.458μF/cm².Conclusion:The impedance spectra of rabbit erythrocytes have presented two characteristic frequency（f-（c1）,f-（c2））,and model-3 is one of the most appropriate equivalent circuit models.更多还原