【摘要】 使昆明小白鼠致脾虚,用双歧杆菌纯制剂治疗后,检测结肠内容物和粪便的肠杆菌、肠球菌、双歧杆菌和乳酸杆菌数量的变化,并结肠进行组织学检查。结果显示:小鼠脾虚后肠杆菌、肠球菌数量明显增多(P<0.05),双歧杆菌、乳酸杆菌数量大量减少(P<0.01);用双歧杆菌纯制剂治疗6d～12d后,肠杆菌、肠球菌数量减少(P<0.05),双歧杆菌、乳酸杆菌大量增多(P<0.01);治疗组结肠组织学观察显示,肠壁肌层厚度增加,杯状细胞数量增多,肠黏膜微绒毛排列紊乱显著改善。更多还原

【Abstract】 After treating with bifidobacterium on spleen-deficiency mice,the quantities of main bacteria in colonic contents and feces of mice such as Enterobacteriaceae,Enterococcus,Bifidobacterium,Bacterocdaceae and Lactobacillus were exmined.The results showed that:the quantity of Bacterocdaceae and enterococcus microbiota in spleen-deficiency mice increased (P<0.05).However,bifidobacteria and Lactobacillus decreased (P<0.01).After treated with Bifidobacterium 6d～12d,the quantity of Bacterocdaceae and enterococcus microbiota in spleen-deficiency mice decreased (P<0.05).However,bifidobacteria and Lactobacillus increased (P<0.01).Observation of histology in colorectal indicated thickness of the intestine muscle layer and quantity of the cup cell increased and villi interstinales arrange order on intestines mucous membrane was improved.更多还原