【摘要】 目的:通过血管内超声(IVUS)对比研究单纯球囊血管成形术(POBA)与切割球囊血管成形术(CBA)的不同作用机制。方法:32例,共34处病变,随机分配病例,20处进入CBA组,14处进入POBA组。采用IVUS分别观察两组术前、术后斑块质和量的变化及临近参考血管的改变。结果:与术前比较,术后两组管腔面积增大程度(△LA)差异无显著性。IVUS下术后血管横截面积的增大程度(△EEM-A)、整个血管横截面积增大占管腔面积增大百分比(△EEM-A/△LA×100%)、病变两端参考血管斑块负荷增大(△PB)之和、CBA组小于POBA组(P<0.01或P<0.001);斑块面积缩小(△PB),CBA组大于POBA组(P<0.01);夹层发生率CBA组小于POBA组(P<0.05)。结论:切割球囊与普通球囊比较两者可获得相似的即刻管腔扩大程度,POBA的主要机制是血管的被动扩张,而CBA的主要机制是斑块的压缩。更多还原

【Abstract】 Objective:This intravascular ultrasound(IVUS) study demonstrsted.The different mechanisms of acute lumen ment between cutting balloon angioplasty(CBA) and plain old balloon angioplasty(POBA).Methods:32 patients after PTCA of which,34 lesions were errolled inthis study mathed 20 lesions in CBA group with 14 lesions in POBA group randomizedy.The procedure was guided by the angigrephy and IVUS was performed before and immediately after balloon diflatation,Difference between pre-and post-procedure of the targrt vessel and reference vessel was recorded with angiography and IVUS.Results:Compariosn of △LA between pre -and post-procedure was no significant difference in CBA and POBA group and IVUS.Compardion of △EEM-A,△EEM-A/△LA×100% and △PB between pre-and post-procedure in CBA was significantly lower in CBA than those in POBA group(P<0.01 or P<0.001);Of △PA in CBA group was significantly longer than that in POBA group(P<0.01);Dissections in CBA were significantly lower than(P<0.05).Conclusions:CBA and POB have the different mechanisons of acute lumen enlargement,with increasing of cessel area(vessel expansion rate,more than 50%) in POBA group and plaque compression in CBA group.更多还原