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采用Logistic回归分析心磷脂抗体与中青年脑梗死的关系
Logistic Regression Analysis on the relationship Anticardiolipin Antibodies and Cerebral Infarction Patients aged 30 to 50 in shanxi Provice,China
【摘要】 目的:探讨心磷脂抗体在中青年脑梗死病因学的地位与作用。方法:采用病例对照研究方法,应用SPSS 11.5统计软件进行单因素及多因素分析,心磷脂抗体的检测采用半定量酶联免疫吸附试验。结果:单因素分析结果提示高血压、中风家族史、吸烟史、高胆固醇血症及心磷脂抗体在两组之间(P<0.05),具有统计学显著性差异。多因素分析结果显示其中高血压、中风家族史、吸烟史与中青年脑梗死关系密切(OR>1,且OR 95%C I不包括1),心磷脂抗体、高胆固醇血症在中青年脑梗死发病中作用小(OR>1,但OR 95%C I包括1)。结论:心磷脂抗体尚不能认为是中青年脑梗死的重要危险因素。
【Abstract】 Objective: To explore the role of serum anticardiolipin antibodies among cerebral infarction.Methods:Case-control study was carried out.Data was analyzed with SPSS11.5 statistical soft.Serum A-CL(Ig-G Ig-M) were determined by half-guantity ELISA.Results: The simple factor analysis showed that the risk factors for cerebral patients aged 30 to 50 was related to hypertension,stoke family history,smoke history,hepercholesterol,A-CL;data showed a statistical significance(P<0.05).Variables in logistic regression showed the more important risk factors are hypertension,stoke family history,smoke history,hepercholesterol,A-CL is not the risk factor.Conclusions: A-CL is not valued as a risk factor for cerebral infarction patients aged 30 to 50.
【Key words】 Anticardiolipin antibodies(A-CL); Cerebral infarction; Risk factor; Logistic regression;
- 【文献出处】 中国民康医学 ,Medical Journal of Chinese People’s Health , 编辑部邮箱 ,2006年03期
- 【分类号】R743.33
- 【被引频次】4
- 【下载频次】91