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乙肝免疫球蛋白联合乙肝疫苗阻断母婴传播136例疗效分析

Analysis on 136 Cases’ Curative Effects of Interdicting Mother-Fetus Transmission by Means of Hepatitis B Immunoglobulin Combined with Hepatitis B Vaccine

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【作者】 李智慧张菊青孙海英

【Author】 LI Zhi-hui~1,ZHANG Ju-qing~1,SUN Hai-ying~2(1.Affiliated Hospital of Beihua University,Jilin 132011,China;2.Beifang Liver and Gall Hospital,Changchun 130062,China)

【机构】 北华大学附属医院北方肝胆医院 吉林吉林132011吉林吉林132011吉林长春130062

【摘要】 孕妇乙型肝炎或表面抗原阳性者对胎儿的影响已得到公认,本文通过对乙型肝炎病毒表面抗原阳性的孕妇在妊娠期间应用乙肝免疫球蛋白(HBIG)进行母婴传播的阻断疗效观察,显示HBIG联合乙肝疫苗对治疗组的阻断成功率为97.1%,疫苗接种成功率为82.4%,而未接种母婴阻断的乙肝病毒感染为15.96%,疫苗接种成功率为57.1%,明显低于治疗组.

【Abstract】 The impact of hepatitis B or positive surface antigen of pregnant women on fetuses is universally acknowledged.This paper is based on the observation of the curative effect of HBIG on pregnant women with positive virus of surface antigen of hepatitis B to interdict mother-fetus transmission during gestation.The results show that the success rate of HBIG combined with hepatitis B vaccine to interdict the transmission was(97.1%);the success rate of vaccination was(82.4%);the hepatitis B virus infection rate without the mother-fetus transmission interdiction vaccination was(15.96%),and the success rate of vaccination was(57.1%),which was obviously lower than that of treatment group.

【关键词】 乙型肝炎表面抗原乙肝免疫球蛋白乙肝疫苗
【Key words】 HBsAgHBIGHepatitis B vaccine
  • 【文献出处】 北华大学学报(自然科学版) ,Journal of Beihua University(Natural Science) , 编辑部邮箱 ,2006年06期
  • 【分类号】R512.62
  • 【被引频次】2
  • 【下载频次】102
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