【摘要】 目的探讨外周血淋巴细胞相对计数和血小板计数与NSCLC晚期患者预后的关系。方法用χ2检验和KaplanMeier生存曲线分析NSCLC晚期死亡患者的外周血淋巴细胞相对计数、血小板计数、生存时间以及和预后的相关性。结果淋巴细胞分类计数≤20%组,中位生存期2个月;淋巴细胞分类计数>20%组,中位生存期6个月。血小板计数≤250×109/L组,中位生存期4个月;血小板计数>250×109/L组,中位生存期3个月,组间均具有显著性差异(P<0.005)。通过KaplanMeier生存曲线和logrank检验,其生存率差异显著。结论血小板增多和淋巴细胞相对计数减少,都是影响NSCLC晚期病人预后不良的重要因素。更多还原

【Abstract】 Objective To study relative lymphocyte count and thromboplastid count in peripheral blood and their relationship with prognosis of NSCLC patients.Methods To analyze these two counts and survival time and their relationship with prognosis by χ 2 test and Kaplan-Meier curves.Results The median survival time in the group of relative lymphocyte count ≤20% is 2 months, that in the other group is 6 months.The median survival time in the group of thromboplastid count ≤250×10 9/L is 4 months,that in the other group is 3 months.There is statistical relationship between their survival rates by Kaplan-Meier curves and log-rank test(P< 0.005).Conclusion Both thrombocytosis and relative lymphocyte count decreasing are independent factors that lead to a worse prognosis of advanced NSCLC patients.更多还原