【摘要】 目的探讨序贯应用甲氨蝶呤(MTX)与米非司酮保守治疗有胎心宫外孕的疗效和安全性。方法序贯应用甲氨蝶呤与米非司酮治疗4例有胎心的宫外孕,观察血β-HCG、肝肾功能、血常规、胃肠道反应。结果在经过1～4个疗程的治疗后,4例有胎心的宫外孕全部获得治愈,除轻微的胃肠道反应、1例ALT、AST轻度升高,无一例出现骨髓抑制和不可逆肝损。结论序贯应用甲氨蝶呤与米非司酮保守治疗有胎心宫外孕是一种安全有效的方法。更多还原

【Abstract】 Objective To investigate the effects and safety of sequential treatments with methotrexate and mifepristone for ectopic pregnancy with fetal cardiac activity.Methods 4 cases of ectopic pregnancy with fetal car- diac activity in our hospital were given by sequential therapy with methotrexate and mifepristone.Serumβ-HCG,liv- er function and renal function,blood routine and gastrointestinal response were observed.Results 4 cases of ectopic pregnancy with fetal cardiac activity with 1～4 periods of sequential treatments were cured.Except light gastroin- testinal response,and one had slight rise of serum ALT level and AST level,no one had rnyelosuppression and heavy hepatic injury.Conclusion The sequential therapy with methotrexate and mifepristone is an effective and safe method for the treatment to ectopic pregnancy with fetal cardiac activity.更多还原