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253株解脲支原体对8种抗生素的体外耐药性分析
Analysis the antibiotic resistance of 253 ureaplasma urealyticum to 8 antibacterial agents in vitro
【摘要】 目的了解阳江地区解脲支原体(UU)的体外耐药情况,指导临床治疗解脲支原体感染。方法对538例可疑泌尿、生殖道解脲支原体感染的患者进行支原体培养、鉴定、药敏试验。结果538例送检标本中共检出253株解脲支原体,药敏试验显示:对8种抗生素的药敏试验敏感性最高的是克拉霉素(73.1%)和罗红霉素(67.9%);对阿奇霉素、交沙霉素、米诺环素、环丙沙星、司帕沙星、多西霉素的耐药率分别为77.1%、70.8%、66.4%、53.8%、43.5%、42.3%,其总耐药率为48.9%。结论对泌尿、生殖道解脲支原体感染的治疗可首选克拉霉素和罗红霉素。
【Abstract】 Objective To analyze the antibiotic resistance of ureaplasma urealyticum(UU) in vitro in Yangjiang,and instruct the clinical treatment for the ureaplasma urealyticum infection.Methods 538 secretion samples of urethra and cervix were collected and cultured ureaplasma urealyticum in vitro,the drug sensitive test of UU from 253 patients was conducted and detected their drug resistance.Results The 253 positives cases were found in 538 samples.The drug sensitive test results were:the highest sensitivity rates were clarithromycin(731%) and roxithromycin(679%).The resistance rates of rest drugs were azithromycin(771%),josamycin(708%),minocycline(664%),ciprofloxacin(538%),sparfloxacin(435%),doxycycline(423%),the total resistance rate was 489%.Conclusion To treat the ureaplasma urealyticum infection,the first choices are clarithromycin and roxithromycin.
- 【文献出处】 中国基层医药 ,Chinese Journal of Primary Medicine and Pharmacy , 编辑部邮箱 ,2006年06期
- 【分类号】R446.5
- 【被引频次】2
- 【下载频次】19