【摘要】 目的了解蛔虫重度流行区采取不同方案的全民化疗措施后,居民个体和群体的蛔虫再感染状况。方法选择鹿塘、大园和杨墅塘3个自然村,全体居民用噻嘧啶首次化疗后,分别间隔3、6和12个月进行重复化疗,并在每年的春、秋季用Kato-Katz法各粪检1次。结果化疗后鹿塘、大园、杨墅塘3个自然村居民蛔虫感染率分别下降53.43%、41.93%和22.62%,人群受精蛔虫卵的比率分别下降50.02%、35.73%和38.30%,化疗1年后的再感染率分别为35.62%、35.48%和50.00%,新感染率分别为16.39%、21.05%和31.94%。人群蛔虫再感染1次和2次的发生率杨墅塘村>大园村>鹿塘村。结论1)试点村人群蛔虫再感染率均比同期新感染率高,蛔虫感染人群比未感染人群表现出更容易发生再感染的倾向;2)间隔6个月的全民化疗方案对控制人群蛔虫的再感染和新感染较经济、有效。更多还原

【Abstract】 Objective To understand the reinfection status of Ascaris lumbricoides after different mass chemotherapy measures were implemented in heavily endemic areas with A.lumbricoides.Methods Residents of the selected villages were treated with pyrantel firstly,repeated chemotherapy was carried out at intervals of 3,6,12 months.Faeces were examined in spring and autumn by Kato-Katz technique to estimate the reinfection rates.Results After mass chemotherapy was adopted,the A.lumbricoides infection rates of residents in 3 villages decreased 53.43%,41.93% and(22.62)% with proportion of fertilized A.lumbricoides eggs decreasing 50.02%,35.73% and 38.30% respectively.One year later,the reinfection rates of A.lumbricoides were 35.62%,35.48% and 50.00% with new infection rates were(16.39)%,21.05% and 31.94%.Conclusion The population ever infected with A.lumbricoides are more easily get reinfection.Mass chemotherapy at intervals of 6 months is more economical and efficiency in controlling reinfection and new infection with A.lumbricoides.更多还原