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MRSA、MSSA对4类抗菌药物耐药基因的研究
Resistance Genes of Antibacterial Agents in MRSA and MSSA
【摘要】 目的探讨耐甲氧西林金黄色葡萄球菌(MRSA)和甲氧西林敏感金黄色葡萄球菌(MSSA)耐药基因存在状况。方法聚合物酶链反应(PCR)法检测mecA、ermA/B/C、aac(6′)/aph(2″)、aph(3′)-Ⅲ、ant(4′,4″)t、etM等耐药基因。结果MRSA检出了mecA、ermA/B/C、aac(6′)/aph(2″)、aph(3′)-Ⅲ、tetM等5种耐药基因。结论MRSA是多重耐药细菌。
【Abstract】 OBJECTIVE To investigate the condition of drug-resistant genes in MRSA and MSSA. METHODS The drug-resistant genes mecA,ermA/B/C,aac(6′)/aph(2″),aph(3′)-Ⅲ,ant(4′,4″) and tetM of MRSA and MSSA were detected by polymerase chain reaction(PCR). RESULTS The 5 kinds of drug-resistant genes,such as mecA,ermA/B/C,aac(6′)/aph(2″),(aph(3′)-Ⅲ) and tetM were positive in MRSA. CONCLUSIONS MRSA is a multi-resistant pathogen.
【基金】 CLON-GEN细菌耐药基因研究专项基金资助(20050101SM)
- 【文献出处】 中华医院感染学杂志 ,Chinese Journal of Nosocomiology , 编辑部邮箱 ,2006年12期
- 【分类号】R378.11
- 【被引频次】3
- 【下载频次】184