【摘要】 目的研究急、慢性牙髓炎症状态下牙髓腔中的细菌内毒素含量及其与临床症状间的关系。方法采用鲎试剂显色技术,定量检测急、慢性牙髓炎症状态下的牙髓腔内细菌内毒素含量,与正常组进行比较,分析内毒素含量与牙髓炎症状态下的临床表现间的关系。结果急、慢性牙髓炎组的内毒素含量有极大差异,前者明显高于后者,且差异具有统计学意义,二者与正常对照组相比,差异也有统计学意义,均明显高于正常对照组。结论内毒素含量与临床表现中的自发痛、放射性疼痛有明显相关。更多还原

【Abstract】 OBJECTIVE To study the amounts of pulpal lipopolysaccharide (LPS) in acute and chronic pulpitis and to analyze the relation between the amounts of LPS in pulpitis and the clinical symptoms. METHODS The Limulus test was used to analyze the amounts of LPS in the root canal of pulpitis, under the condition of acute and chronic pulpitis. RESULTS The amounts of LPS in 23 cases of acute pulpitis were found significantly higher than that in 22 cases of chronic pulpitis, P<0.0001; the amounts of LPS in acute or chronic pulpitis were significantly higher than those in the normal control, P<0.0001; the mean value of acute and chronic pulpitis was (9.34±0.37) and (4.45±0.85)μg/ml, respectively, the control was (0.018±0.04)mg/ml. CONCLUSIONS The results also showed that the spontaneous and radial pain has the closest relationship with the amounts of LPS.更多还原