【摘要】 自我们的祖先发明人痘、琴纳(Jenner)发明牛痘到今天,疫苗在防治许多疾病中的功绩已为世人所公认。1995年美国纽约科学院召开专门研讨脱氧核糖核酸(DNA,以下简称核酸)疫苗会议,称之为疫苗学的新纪元和疫苗的第三次革命。第一次疫苗革命是19世纪末以巴斯德(Pasteur)为代表的灭活疫苗和减毒活疫苗。第二次疫苗革命是20世纪80年代采用核酸重组技术和蛋白化学技术制备的亚单位疫苗。更多还原

【Abstract】 Since the Chinese inuented the uaniolation with human pox vaccine and Jenner invented the vaccine for cowpox, the great achievements of vaccination in preventing and treating many diseases are universally acknowledged. In 1995, the New York Academy of Sciences of America sponsored a symposium on DNA (deoxyribonucleic acid) vaccine, which is called the third revolution of vaccine and new epoch for vaccinology. The first revolution was the invention of inactivated vaccines and live attenuated vaccines represented by Pasteur at the end of the nineteenth century. The second one was the subunit of vaccine prepared by DNA recombination technique and techniques of protein chemistry in 1980s.更多还原