【摘要】 目的探讨肺动脉高压患者右室机械活动延迟与右室收缩功能之间的关系。方法51例肺动脉高压患者按肺动脉高压程度分为轻、中、重3组,并选取30名健康人为对照组,采用定量组织多普勒技术(QTVI)取心尖四腔切面分别测量右室三尖瓣环、室间隔三尖瓣环收缩期达峰时间,二者差值为右室机械收缩延迟时间(RV-IVSd);常规二维超声同一切面测量右室舒张末期面积、收缩末期面积,计算出右室面积变化分数(RVa%)。结果 (1)与对照组比较,轻、中、重度肺动脉高压组RV-IVSd 明显延迟(P<0.05),且肺动脉压力越高,延迟越明显;(2)轻度组 RVa%与对照组间差异无统计学意义(P>0.05),而中、重度组 RVa%低于对照组(P<0.05);(3)肺动脉高压各组 RV-IVSd 与RVa%相关性均良好(r=-0.79;r=-0.66;r=-0.80)。结论 RV-IVSd 可在一定程度上反映右心收缩功能,为超声评估右室收缩功能提供了一种新指标。更多还原

【Abstract】 Objective To investigate the relationship between right ventricular(RV)mechanical delay and RV dysfunction in patients with pulmonary hypertension(PH).Methods A total of 51 patients with PH were divided into mild,moderate and high PH groups and 30 healthy volunteers served as control group.RV mechanical delay(defined as the difference in time to peak systolic annular velocity between the RV free wall and the ventrieular septum)and RV fractional area change were obtained on apical four chamber view with Quantitive Tissue Velocity Imaging(QTVI).Results RV mechanical delay increases in proportion to pulmonary pressure.RV fractional area change was similar between control and mild PH patients while significantly reduced in moderate and high PH patients compared to controls.RV mechanical delay significantly correlated to RV fractional area change in all PH groups(r=-0.79;r=-0.66;r= -0.80,all P<0.05).Conclusion RV mechanical delay measured by QTVI can be used to evaluate RV dysfunction in patients with pulmonary hypertension.更多还原