【摘要】 目的本研究对<4个月阻塞性黄疸婴儿十二指肠内的胆红素进行光吸收值动态监测,评价光吸收值在胆道闭锁诊断中的意义。方法研究对象分为胆道闭锁患儿(biliaryatresia,BA)17例(男11例,女6例;年龄2~16周,平均5.7周)及婴儿肝炎综合征患儿(infantilehepatitissyn-drome,IHS)20例(男14例,女6例;年龄3~7周,平均5周)。37例患儿接受了Bilitec十二指肠内胆红素光吸收值的监测,观察原始光吸收值曲线图,分析、比较最高光吸收值、光吸收值≥0.14U及≥0.25U的时间百分比。结果胆道闭锁组的光吸收值明显低于婴儿肝炎综合征组。结论十二指肠内胆红素光吸收值监测可为鉴别BA与IHS提供客观依据。更多还原

【Abstract】 Objective To investigate the reliability of the duodenal bilirubin absorbance values in the diagnosis of biliary attresia (BA). Methods Bilirubin exposure in the duodenum was measured with the Bilitec 2000 device in BA group (11 males and 6 females; aged from 2 to 16 weeks,average 5.7 weeks) and infantile hepatitis syndrome (IHS) group (14 males and 6 females; aged from 3 to 16 weeks, average 5 weeks).The original charts of bilirubin absorbance values were recorded, and investigation data included maximal absorbance value, percentages of total time absorbance ≥0.14U and 0.25 U were analyzed with the modified program of Esophogram software. Results The percentages of total time absorbance ≥0.14U, 0.25U and the maximal absorbance value in BA infants were significantly lower than those in IHS infants. Conclusions Dynamic observation of the duodenal bilirubin absorbance value can provide reliable evidence to the early diagnosis of BA.更多还原