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肝脏原发上皮-肌上皮癌首例报告

The first case of primary epithelial-myoepithelial carcinoma in the liver

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【作者】 刘勇桑新亭高维生毛一雷刘跃武刘洪沨杨志英杨松竹钟守先黄洁夫

【Author】 LIU Yong, SANG Xin-ting, GAO Wei-sheng, MAO Yi-lei, LIU Yue-wu, LIU Hong-feng, YANG Zhi-ying, YANG Song-zhu, ZHONG Shou-xian, HUANG Jie-fu. Department of Surgery, Peking Union Medical College Hospital,Peking Union Medical College, Chinese Academy of Medical Sciences,Beijing 100730, China

【机构】 中国医学科学院中国协和医科大学北京协和医院外科中国医学科学院中国协和医科大学北京协和医院外科

【摘要】 目的报道首例原发于肝脏的上皮-肌上皮癌患者。方法描述我院收治的1例经病理学明确诊断的肝脏原发的上皮-肌上皮癌的临床表现、影像学改变、病理特点等。患者女性,37岁,体检发现右肝直径10cm肿瘤,接受多项影像学(B超、CT、MRI)检查、反复肝脏穿刺活检和甲胎蛋白检查,但均无特异性,术前未能明确诊断。结果行右半肝切除,术后病理检查显示双套管样结构,免疫组化染色证实为上皮-肌上皮癌。结论该肿瘤在肝脏原发为罕见,术前诊断困难,需术后病理及免疫组化染色确诊。

【Abstract】 Objective To report the first case of primary epithelial-myoepithelial carcinoma (EMC) in the liver. Methods The clinical manifestations, imageologic characteristics, and histopathological changes of EMC in this case were described. The patient was a thirty-seven-year old female. A 10 cm lesion was detected in the right liver upon a routine examination. Following that, the CT scan, magnetic resonance imaging (MRI), repeated puncture biopsies, and serum alpha-fetoprotein (AFP) detection were done with no specificity and significance found. Results Right hemi-hepatectomy was performed. The special double catheterization cannula was found in the histopathological examination, and the final diagnosis of EMC was proven by immuno-histochemical staining. Conclusions Primary EMC is difficult to be finally diagnosed prior to the surgery. The diagnosis can be confirmed using pathological examination and immuno-histochemical staining of the specimen.

  • 【文献出处】 中华外科杂志 ,Chinese Journal of Surgery , 编辑部邮箱 ,2006年21期
  • 【分类号】R735.7
  • 【被引频次】5
  • 【下载频次】102
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