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肝脏原发上皮-肌上皮癌首例报告
The first case of primary epithelial-myoepithelial carcinoma in the liver
【摘要】 目的报道首例原发于肝脏的上皮-肌上皮癌患者。方法描述我院收治的1例经病理学明确诊断的肝脏原发的上皮-肌上皮癌的临床表现、影像学改变、病理特点等。患者女性,37岁,体检发现右肝直径10cm肿瘤,接受多项影像学(B超、CT、MRI)检查、反复肝脏穿刺活检和甲胎蛋白检查,但均无特异性,术前未能明确诊断。结果行右半肝切除,术后病理检查显示双套管样结构,免疫组化染色证实为上皮-肌上皮癌。结论该肿瘤在肝脏原发为罕见,术前诊断困难,需术后病理及免疫组化染色确诊。
【Abstract】 Objective To report the first case of primary epithelial-myoepithelial carcinoma (EMC) in the liver. Methods The clinical manifestations, imageologic characteristics, and histopathological changes of EMC in this case were described. The patient was a thirty-seven-year old female. A 10 cm lesion was detected in the right liver upon a routine examination. Following that, the CT scan, magnetic resonance imaging (MRI), repeated puncture biopsies, and serum alpha-fetoprotein (AFP) detection were done with no specificity and significance found. Results Right hemi-hepatectomy was performed. The special double catheterization cannula was found in the histopathological examination, and the final diagnosis of EMC was proven by immuno-histochemical staining. Conclusions Primary EMC is difficult to be finally diagnosed prior to the surgery. The diagnosis can be confirmed using pathological examination and immuno-histochemical staining of the specimen.
【Key words】 Liver; Myoepithelioma; Epithelial neoplasms, malignant; Pathology;
- 【文献出处】 中华外科杂志 ,Chinese Journal of Surgery , 编辑部邮箱 ,2006年21期
- 【分类号】R735.7
- 【被引频次】5
- 【下载频次】102