【摘要】 目的探讨颈动脉粥样硬化与缺血性脑血管病的关系。方法以2001年6月至2004年12月在我院住院的1583例急性缺血性脑血管病患者为研究对象,应用超声诊断仪检测双侧颈动脉,采用非条件Logistic回归分析颈动脉粥样硬化的危险因素及与缺血性脑血管病的关系。结果86.5%(1369/1583)患者存在不同程度颈动脉粥样硬化;脑梗死组颈动脉粥样硬化患病率(1087/1266,85.9%)较短暂性脑缺血发作组(198/317,62.5%)高。颈动脉粥样硬化病变特点以斑块居多(1286/1583,81.2%),而中重度狭窄发生率较低(214/1583,13.5%);颈动脉斑块以颈总动脉分叉处最多见(665/1286,51.7%)。斑块发生率及颅外段颈动脉狭窄程度与脑血管病危险因素有明显相关性。结论佛山地区缺血性脑血管病患者颈动脉粥样硬化病变可能以斑块居多,颈动脉粥样硬化与缺血性脑血管病有关。更多还原

【Abstract】 Objective To discuss the relationship between carotid atherosclerosis and the ischemic cerebrovascular disease(ICVD).Methods 1583 subjects with acute ICVD enrolled from June 2001 to December 2004 underwent carotid artery duplex ultrasonography.Logistic regression was performed to analyze the relationship between carotid atherosclerosis and ICVD.Results 86.5%(1369/1583)of all the patients had a varying degree of carotid atherosclerosis,in which the occurrence of the atherosclerotic plaques(1286/1583,81.2%)higher than that of stenosis of the extracranial carotid(214/1583,13.5%).There was a significant difference in the incidence of carotid atherosclerosis between patients from the TIA group(198/317,62.5%)and from the cerebral infarction group(1087/1266,85.9%).Carotid atherosclerotic plaques were most commonly seen in the bifurcations of the common carotid artery(665/1286,51.7%).The severity of stenosis of the extracranial carotid and the formation of the atherosclerotic plaques were significantly correlated to the risk factors of cerebrovascular disease.Conclusions Atherosclerotic plaques are dominant characteristics of carotid atherosclerosis in the patients with ICVD in Foshan.There is a positive correlation between carotid atherosclerosis and ICVD.更多还原