【摘要】 对适宜¹³¹Ⅰ治疗的儿童和青少年甲亢患者进行治疗前后的疗效观察研究。临床确诊及对抗甲亢药物耐药或有禁忌证的31例患者接受了¹³¹Ⅰ治疗。其中15例痊愈,11例明显好转,5例甲减；18例突眼患者中,8例突眼基本恢复正常,4例缓解,5例无变化和1例加重。对不宜行抗甲亢药物治疗的10岁以上甲亢患者来说,¹³¹Ⅰ是一种相对安全、有效的治疗方法。更多还原

【Abstract】 The efficacy of ¹³¹I treatment of hyperthyroidism in children and adolescents was evaluated. Being unsuitable for medical therapy,31 patients （aged 11-18 years） with hyperthyroidism received ¹³¹I treatment with a dose of 0.925-3.33 MBq/g of thyroid and were followed-up for 20 to 76 months.Fifteen patients were euthyroid,5 suffered from late-onset hypothyroidism,and 11 were still hyperthyroid,but their symptoms and signs of hyperthyroidism were markedly improved.Of the 18 patients with thyroid-associated ophthalmopathy （TAO）,8 patients recovered,4 were improved,TAO in 1 patients deteriorated and in S patients remained unchanged.¹³¹I is a relative safe and effective treatment for children and adolescents above 10 years old with hyperthyroidism,being unsuitable for medical therapy.更多还原