【摘要】 体外培养SW872细胞,油酸诱导其分化为成熟的脂肪细胞,然后加入重组人白细胞介素6 (IL-6)观察其对SW872成熟脂肪细胞促酰化蛋白(ASP)分泌的影响。结果显示0.6mmol/L油酸刺激72 h能成功诱导SW872前脂肪细胞分化为成熟的脂肪细胞；IL-6对SW872成熟脂肪细胞ASP的分泌具有明显的抑制作用,且表现为时间和剂量依赖效应。更多还原

【Abstract】 SW872 cells were cultured in vitro with oleic acid and differentiated into mature adipocytes. The role of interleukin-6(IL-6)in the secretion of acylation-stimulating protein(ASP)in mature SW872 adipocytes was observed.The results suggested that IL-6 significantly inhibited ASP secretion into the media in a dose-and time-dependent manner in mature SW872 adipocytes.更多还原