【摘要】 本研究探讨Graves病(GD)患者尿碘水平与外周血细胞因子和单个核细胞(PBMC)表面抗原的关系。结果表明高碘摄入可能加重GD突眼、甲状腺肿大等症状,IL-1β等细胞因子和PBMC表达的HLA-DR、CD80异常与高碘导致的免疫紊乱可能有一定关系。更多还原

【Abstract】 The relationship among iodine intake and serum cytokine level and expressions of antigens on peripheral blood monocytes (PBMC) of GD patients was investigated. The results indicated that high iodine intake may aggravate clinical symptoms such as thyrocele and ophthalmopathy in GD patients. The abnormal increase of cytokine IL-1β and expressions of CD80 and HLA-DR on PBMC seem to be involved in immune disturbance.更多还原