【摘要】 目的探讨电针刺激对腔隙性脑梗死后抑郁状态的影响。方法本研究共选取75例腔隙性脑梗死后抑郁患者,将其随机分为药物治疗组(药物组)和针药治疗组(治疗组)。药物组给予氟西汀(百优解) 20 mg/d,治疗组在应用氟西汀的同时,还给予电针刺激干预。分别于治疗前、治疗后第2,4周时采用汉密尔顿抑郁量表(HAMD)、中国卒中量表(CSS)及Barthel指数量表(BI指数)对患者进行疗效评定。结果治疗组患者经2周治疗后,其抑郁症状明显改善,HAMD评分降低；治疗4周后,2组患者抑郁症状均较治疗前明显好转；进一步分析后发现,治疗组患者HAMD评分明显低于药物组,组间差异具有统计学意义(P＜0．05),并且治疗组患者神经功能改善及日常生活活动能力提高的时间均早于药物组(P＜0．05)。结论电针联合抗抑郁药物治疗腔隙性脑梗死后抑郁具有起效时间快、疗效佳及不良反应少等优点,值得临床推广、应用。更多还原

【Abstract】 Objective To investigate the therapeutic effects of electroacupuncture (EA) on post stroke depres- sion (PSD) after lacunar infarction (LI).Methods Seventy-five PSD patients with lacular infarction were recruited and randomly divided into a control group and an EA group.All patients were treated with Fluoxetine,in addition to EA treat- ment in the EA group.Then all patients were evaluated using the Hamilton Depression Scale (HAMD),the Chinese stroke scale (CSS) and the Barthel Index (BI).The evaluations were carried out at 0,14 and 28 days.Results Depression symptoms (DSs) in the EA group were improved by day 14 of the treatment,and their HAMD scores had decreased.DSs in both groups had improved significantly by day 28,and the HAMD scores in the EA group were then significantly lower than those in the control group.Improvements in neurological impairment and in the activities of daily living were observed earlier in the EA group.Conclusion The combination of EA and Fluoxetine is helpful for PSD with complex patho- genesis and clinical symptoms.Therapeutic effects are enhanced and side effects are reduced.更多还原