【摘要】 目的探讨高压氧(HBO)治疗后立即放射治疗宫颈癌的疗效和应用价值。方法随机选择确诊为Ⅱ～Ⅲ期宫颈癌的患者58例,其中28例设为HBO组,30例为对照组。2组均常规采用60Co外照射+腔内后装治疗,HBO组在每次放射治疗前行HBO治疗,出舱后25 min内行放射治疗。结果HBO组完全缓解率(CR)为75．0％,总有效率(CR+PR)为92．8％,3年生存率为71．4％,局部复发率为10．7％,与对照组比较,差异有统计学意义(P<0．05);而且HBO组放射治疗副反应及并发症亦明显减少。结论HBO治疗后立即放射治疗是提高宫颈癌放射治疗疗效的有效途径。选择合理的对象和应用时机是提高疗效的关键环节。更多还原

【Abstract】 Objective To explore the clinical value when treating cervical cancer of supplementing radiotherapy with hyperbaric oxygen treatment. Methods Fifty-eight cervical cancer patients were randomly divided into 2 groups; the HBO group (n=28) received radiotherapy combined with hyperbaric oxygen treatment; a control group (n = 30) received only radiotherapy. Results The complete response rate (CR) of the HBO group was 75.0% , the partial response rate (PR) was 7.1% ,the effective rate(CR + PR) was 92.8% , the total 3 year survival rate was 71.4% , the local recurrence rate was 10.7% , and all of these results were significantly different from the controls (P <0.05). Conclusion Hyperbaric oxygen treatment can increase the effectiveness of radiotherapy in the treatment of cervical cancer.更多还原