【摘要】 目的研究中药五倍子化学成分对早期釉质龋表面显微硬度的影响。方法应用离体牛切牙制备人工釉质龋标本60个,编号后采用抽签法随机分为6组:NaF 组(阳性对照)、总鞣质(GCE)组、GCE-B 组、GCE-B1组、GCE-B2组及去离子水组(阴性对照),进行体外 pH 循环实验,采用显微硬度计测定标本脱矿前后和 pH 循环后的硬度值,观察釉质表面显微硬度的变化。结果GCE、GCE-B 和 GCE-B1 3组能明显提高早期釉质龋的表面显微硬度,GCE-B2对釉质龋的表面显微硬度无明显影响。结论五倍子化学成分 GCE、GCE-B 和 GCE-B1具有潜在的防龋功效。更多还原

【Abstract】 Objective To evaluate the effect of chemical compounds extracted from Galla chinensis on enamel surface rehardening in vitro.Methods Sixty bovine enamel blocks with early carious lesions were randomly divided into six groups:group1 treated NaF(positive control);group2 with GCE;group3 with GCE-B;group4 with GCE-B1;group5 with GCE-B2 and group6 with deionized water(negative control). The lesions were subjected to a pH-cycling regime for 12 days.Surface enamel microhardness was measured on the enamel blocks before and after demineralization.After pH-cycling,and the percentage of surface microhardness recovery(SMHR)was calculated.Results Obvious increase of the surface hardness of the enamel was observed in all the treatments except GCE-B2 and deionized water(P<0.05).Conclusions The present study demonstrates the potential of the three GCEs(GCE,GCE-B and GCE-B1)to effect net rehardening of artificial carious lesions under dynamic pH-cyclic conditions.更多还原