节点文献

18F-脱氧葡萄糖PET-CT检测食管癌病变长度的临床价值

Value of 18FDG PET-CT in defining the length of esophageal cancer

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 袁双虎于金明于甬华杨新华付政杨国仁郭洪波王晓航周英智陈少卿

【Author】 YUAN Shuang-hu~* YU Jin-ming YU Yong-hua Yang Xin-hua FU Zheng YANG Guo-ren GUO Hong-bo WANG Xiao-hang ZHOU Ying-zhi CHEN Shao-qing ~*Department of Radiation Oncology,Shandong Cancer Hospital,Jinan 250117,China

【机构】 山东省肿瘤医院放疗科山东省肿瘤医院核医学科山东省肿瘤医院胸外科山东省立医院胸外科山东大学山东省肿瘤医院放疗科 250117济南 天津医科大学肿瘤学博士研究生

【摘要】 目的评价18F-脱氧葡萄糖(FDG)PET-CT诊断食管癌病变长度的临床价值,并和其他检测方法比较。方法选择食管癌患者32例,其中胸上段食管癌1例,胸中段22例,胸下段9例。术前分别行食管镜、食管钡餐、CT和FDG PET-CT检查,并检测食管癌原发灶病变位置和长度。1周内行食管癌手术,手术大体标本与检查结果比较。结果食管钡餐、CT、FDG PET-CT分段与大体标本全部符合,而食管镜检查有2例分段与大体标本不符合。食管镜、食管钡餐、CT、PET-CT所示食管癌病变长度与大体标本的相关系数分别是0.741、0.746、0.870、0.876(P值均为0.000);所示食管癌原发灶长度分别为(3.8±1.4)、(4.1±1.5)、(4.4±1.6)、(5.3±1.9)和(4.7±1.7)cm,4种检查结果与大体标本差异均有统计学意义(P=0.000、0.007、0.025、0.001),病变长度从小到大依次为食管镜、食管钡餐、CT、大体标本、PET-CT。但考虑到标本离体后有一定程度的回缩,实际病变长度与PET-CT最接近。结论PET-CT较准确的显示食管癌病变实际长度,有一定临床价值。对手术病例,PET-CT可用于指导术者选择食管癌切除的剖胸径路及食管切除长度;对放疗病例,PET-CT有助于指导放疗靶区的精确确定。

【Abstract】 Objective To assess the value of 18-fluoro-deoxy-glucose positron emission-CT(FDG PET-CT) in defining the length of primary esophageal cancer.Methods Thirty-two patients had underg- one esophagoscopy,esophagography and FDG PET-CT scans one week before esophagectomy.There was one tumor located in the upper thoracic esophagus,22 in the middle thoracic esophagus,and 9 in the lower tho- racic esophagus.The location and length of primary lesion of the tumor was determined by esophagoscopy, esophagography,and FDG PET-CT.The length of the abnormality seen on the CT portion of the PET-CT scan was determined separately and independently by two radiologists.All results were compared with the resected specimen.Results According to esophagography,CT and PET-CT,all lesion lengths were compared with that of the resected specimen.It was found that the tumor location determined by esophagoscopy was not in accordance with the resected specimen in 2 patients.The mean length of the primary tumor,being from short to long,were (3.8±1.4),(4.1±1.5),(4.4±1.6),(5.3±1.9) and (4.7±1.7) cm,as determined by esophagoscopy,esophagography,CT,actral length of the resected specimen and PET-CT.Compared with the resected specimen,there was obvious difference (P=0.000,0.007,0.025,0.001).Considering that there might be some kind of shrinkage in the resected specimen (about 83.59%,as reported by Ma et al), we rectified the length of resected specimen and compared with other findings again.It was found that insig- nificant difference existed between PET-CT and rectified length value of the resected specimen (P=0.082). Conclusions FDG PET-CT is effective in the length determination of primary esophageal cancer.It may he used to determine the length of esophagus to be resected for patients indicated for esophagectomy.It may also be used to ac- curately delineate the gross tumor volume for patients eligible for radiotherapy.

  • 【文献出处】 中华放射肿瘤学杂志 ,Chinese Journal of Radiation Oncology , 编辑部邮箱 ,2006年05期
  • 【分类号】R735.1
  • 【被引频次】88
  • 【下载频次】425
节点文献中: 

本文链接的文献网络图示:

本文的引文网络