【摘要】 目的探讨体外受精-胚胎移植中移植胚胎在子宫腔中的深度对临床妊娠率的影响。方法在腹部B超引导下测量92例胚胎移植患者的移植胚胎与宫底之间的距离,并取其距离平均数0．75 cm进行分组。组1(44例)的移植胚胎距离宫底>0．75 cm,组2(48例)的移植胚胎距离宫底≤0．75 cm。分析两组的妊娠结局。结果组1、组2患者的年龄分别为(32±3)和(31±4)岁,获卵数分别为(14±7)和(14±6)个,移植胚胎数分别为(2．3±0．6)和(2．2±0．5)个,两组分别比较,差异均无统计学意义(P>0．05)。组2的移植胚胎距宫底的距离平均为(0．50±0．21)cm,明显小于组1的(1．02±0．21)cm,两组比较,差异有统计学意义(P<0．01);但组2的临床妊娠率为58．3％(28／48),显著高于组1的36．4％(16／44),两组比较,差异有统计学意义(P<0．05)。组2的胚胎植入率(33．0％)也高于组1(22．2％),但两组比较,差异无统计学意义(P>0．05)。结论胚胎移植的深度对临床妊娠率有显著影响,移植胚胎的位置在子宫底处更有利于提高临床妊娠率。更多还原

【Abstract】 Objective To detect whether the depth of embryo transfer has influence on pregnancy outcome in in vitro fertilization-embryo transfer (IVF-ET). Methods The distance between the high echogenic transfer dot and the fundal endometrium was measured under guidance of transabdominal ultrasound. The average distance 0. 75 cm was used to divide patients into two groups. Group 1 included 44 patients with a distance > 0. 75 cm, while group 2 had 48 patients with a distance≤0. 75 cm. Results There were no significant differences in the average age (32±3 versus 31±4) , the mean number of oocytes retrieved( 14±7 versus 14±6) , and the mean number of embryos transferred (2. 3±0. 6 versus 2. 2±0. 5) between groups 1 and 2. The distance to the fundal endometrium in group 2 was (0. 50±0. 21) cm, significantly smaller than that of group 1 (1. 02±0. 21) cm (P < 0. 01). However, pregnancy rate was significantly higher (P<0.05)in group 2 (58.3% , 28/48) than in group 1 (36.4%, 16/44). Although implantation rate in group 2 (33. 0% , 35/106) was higher than group 1 (22. 2% , 22/99) , the difference was not significant. Conclusion Pregnancy outcome may be affected by the depth of embryo transfer, and the fundal endometrium is a favorable region for embryo deposition.更多还原